Oral polio drops linked to paralysis in India
"Now that India has been polio-free for over six years, we may be able to reduce non-polio AFP by further reducing pulse polio rounds.
The study found the paralysis rate to be as high as 30 per 100,000 people in Bihar and Uttar Pradesh.The study showed that the number of pulse polio rounds (immunisation campaigns) conducted in a state had a "high correlation" with the non-polio paralysis rate.
Currently, the wild polio virus, which attacks the nervous system leading to childhood paralytic disease, is confined to Afghanistan, Nigeria and Pakistan The oral vaccine uses live but weakened poliovirus strains to produce antibodies that protect children from being infected with ‘wild’ or naturally-occurring polio viruses.
"While the mechanism involved is speculative, our findings support the hypothesis that the frequency of pulse polio administration is directly or indirectly related to the incidence of non-polio AFP," the authors write.
"Puliyel points out that the increase in non-polio AFP was noticed only because of excellent surveillance and meticulous recording of data by government agencies.